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OIE: Influenza A viruses of high pathogenicity (infection with H5N1) (non-poultry including wild birds) (2017-), Japan
General information Report type: immediate notification Started on: 2 Jan 2022 End Date: 2 Jan 2022 Confirmed on: 22 Jan 2022 Last occurrence: 25 Mar 2011 ...
submitted by kickingbird at Feb, 8, 2022 12:13 PM via(https://wahis.oie.int/#/report-info?reportId=48019)

Article

Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions
For an efficacious vaccine immunogen, influenza hemagglutinin (HA) needs to maintain a stable quaternary structure, which is contrary to the inherently ...
submitted by kickingbird at Feb, 9, 2022 11:22 AM via(https://www.pnas.org/content/119/6/e2115379119)

Broad neutralizing antibody-based strategies to tackle influenza
Influenza viruses cause occasional pandemics and annual epidemics, thus persist as a threat to human society. The high variability of viral envelope proteins ...
submitted by kickingbird at Feb, 9, 2022 11:21 AM via(https://www.sciencedirect.com/science/article/abs/pii/S1879625722000141)

Environmental factors and spatiotemporal distribution characteristics of the global outbreaks of the highly pathogenic avian influenza H5N1
The spread of highly pathogenic avian influenza H5N1 has posed a major threat to global public health. Understanding the spatiotemporal outbreak characteristics ...
submitted by kickingbird at Feb, 8, 2022 12:53 PM via(https://link.springer.com/article/10.1007/s11356-022-19016-1)

139D in NS1 Contributes to the Virulence of H5N6 Influenza Virus in Mice
H5N6, the highly pathogenic avian influenza A virus (IAV) of clade 2.3.4.4, causes global outbreaks in poultry. H5N6 has become the dominant IAV subtype ...
submitted by kickingbird at Feb, 8, 2022 12:52 PM via(https://www.frontiersin.org/articles/10.3389/fvets.2021.808234/full)

Generation of a pdmH1N1 2018 Influenza A Reporter Virus Carrying a mCherry Fluorescent Protein in the PA Segment
Influenza A virus (IAV) is a major human pathogen associated with significant morbidity and mortality worldwide. Through serial passage in mice, we generated ...
submitted by kickingbird at Feb, 8, 2022 12:50 PM via(https://www.frontiersin.org/articles/10.3389/fcimb.2021.827790/full)

Prevalence of avian influenza H5, H7, and H9 viruses in commercial layers in Karachi, Pakistan
Background: Avian influenza viruses (AIVs) cause significant harm to the poultry industry due to mortality as well as high morbidity along with the risk ...
submitted by kickingbird at Feb, 8, 2022 12:48 PM via(https://ijvr.shirazu.ac.ir/article_6347.html)

The molecular determinants of antigenic drift in a novel avian influenza A (H9N2) variant virus
Background: In early 2020, a novel H9N2 AIV immune escape variant emerged in South China and rapidly spread throughout mainland China. The effectiveness ...
submitted by kickingbird at Feb, 8, 2022 12:47 PM via(https://virologyj.biomedcentral.com/articles/10.1186/s12985-022-01755-9)

Intradermal administration of influenza vaccine with trehalose and pullulan-based dissolving microneedle arrays
Most influenza vaccines are administered via intramuscular injection which has several disadvantages that might jeopardize the compliance of vaccinees. ...
submitted by kickingbird at Feb, 8, 2022 12:46 PM via(https://jpharmsci.org/article/S0022-3549(22)00042-9/fulltext)